ecopa | archive | eSi workshop 2008: presentations
	eSi workshop 2008: presentations Pueblo Acantilado near Alicante, Spain, October 17-19 2008 "Functional HepaRG Cells: A breakthrough breakthrough in 3-R research?" André Guillouzo University University of Rennes 1and Inserm U620 PDF: download this presentation (2 MB) "Hepatocyte in vitro gene expression systems: what is the reason for differences between in vivo and and in vitro systems?" Markus Schug, Dipl. Pharm. Leibniz Research Centre for Working Environment and Human Factors (IfADo) PDF: download this presentation (292 kb) "Non-genotoxic hepatocarcinogens specifically target mitochondria and gap junctions" Tatyana Doktorova PhD student Vrije Universiteit Brussel Promotors: Prof. Dr. Vera Rogiers, Prof. Dr. Tamara Vanhaecke, Dr. Mathieu Vinken PDF: download this presentation (416 kb) "Cytotoxic and genotoxic effects of two heterocyclic amines in functional human hepatoma HepaRG cells" Julie Dumont 1, Rozenn Jossé 1, Valérie Fessard 2, André Guillouzo 1 1 - Inserm U620 , Rennes 1 University, Rennes, France 2 - AFSSA, Unit of genetic toxicology of food contaminants, Fougères, France PDF: download this presentation (592 kb) "Markers of proliferation and differentiation in human keratinocyte models" Yves Poumay Cell & Tissue Laboratory - URPHYM University of Namur (Facultés Universitaires Notre-Dame de la Paix) Namur, Belgium PDF: download this presentation (5.8 MB) "MicroRNAs: novel regulators in skin research" Eniko Sonkoly, Andor Pivarcsi KI, Department of Medicine, Unit of Dermatology and Venerology PDF: download this presentation (1.1 MB) "Use of gene silencing in skin models" Michael Mildner PDF: download this presentation (4.3 MB) "Safety aspects of skin penetration of nanoparticles in topically applied cosmetics / pharmaceuticals" A. Patzelt, H. Richter, W. Sterry, J. Lademann Center of Experimental and Applied Cutaneous Physiology (CCP) PDF: download this presentation (2.8 MB) "Nanoparticle induced pulmonary toxicity" N.J. Guppy, Institute of Cellular and Molecular Science, QMUL, London, UK Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany PDF: download this presentation (1.2 MB) "Toxicological Studies Of Poly (Anyhydride) Nanoparticles For Oral Drug Delivery" Patricia Ojer Ojer, Dr. Juan Manuel Irache1, Dra. Adela López de Cerain2 Department of Pharmacy and Pharmaceutical Technology1 & Department of Nutrition and Food Sciences, Physiology and Toxicology2 University of Navarra PDF: download this presentation (1.2 MB) "Important issues in immunotoxicity testing of chemicals" Pr Marc Pallardy Toxicologie and INSERM UMR-S 749, Faculté de Pharmacie, Châtenay-Malabry, France PDF: download this presentation (2.6 MB) "Development Of Iv Vitro Strategies For Studying T-Cell Mediated To Immunological Reactions To Drugs " Enrique Gomez Research Laboratory Fundacion IMABIS-Carlos Haya Hospital Málaga, Spain PDF: download this presentation (2.1 MB) "In-vitro quantitation of sensitizing potential" Reinhard Wanner Institute of Clinical Pharmacology and Toxicology Charité, Berlin, Germany PDF: download this presentation (1.6 MB) "Reactivity studies to complement the development of alternative methods for the prediction of skin sensitization: the case of formaldehyde and formaldehyde releasers" M. Kireche, E. Giménez-Arnau, J.P. Lepoittevin Institut de Chimie de Strasbourg UniversitéLouisPasteur-CNRS Université Louis Pasteur-CNRS Laboratoire de Dermatochimie Strasbourg, France PDF: download this presentation (204 kb) "In vitro differentiation of skin sensitizers by cell signaling pathways" Lydia-Mareen Koeper, Bayer HealthCare AG, Toxicology PDF: download this presentation (968 kb) "Identification of cell responses induced by a sensitizer in a" Aurélie Frankart, S. Lambert, A. Coquette, K. Schroeder and Prof. Yves Poumay PDF: download this presentation (1,5 MB) "About Pipelines and Shifting paradigms: biopharmaceuticals versus low molecular weight drugs" Prof. Dr. Daan, J.A. Crommelin, Scientific Director TI Pharma, a Public Private Partnership, Leiden and Dept. Pharmaceutics, UIPS, UU PDF: download this presentation (2 MB) "Prednisolone-treatment induces hepatic insulin resistance in C57Bl/6J mice, measured by a newly develobody glucose test" Anke Laskewitz Lab pediatrics Center for liver, digestive and metabolic diseases University medical center Groningen The Netherlands PDF: download this presentation (676 kb) "A suitable delivery system is key in the concept of siRNA-mediated treatment" R. Vandenbroucke Laboratory of General Biochemistry and Physical Pharmacy Ghent Research Group on Nanomedicines (GRGN) Department of Pharmaceutics Ghent University, Belgium PDF: download this presentation (2.9 MB) "Molecular imaging in vitro and in vivo" Tony Lahoutte, MD PhD Free University Brussels PDF: download this presentation (1.9 MB) "An alternative method in (live) cell sampling" Renate Burgemeister Laser Microdissection from Carl Zeiss PDF: download this presentation (11.3 MB) "COMICS: developing high throughput comet assays for DNA damage and DNA repair" Amaya Azqueta on behalf of COMICS partners Department of Nutrition University of Oslo PDF: download this presentation (2 MB) "Use of flow-based assays to monitor drugs with antithrombotic, anticoagulant or anti-inflammatory potential" J. Heemskerk, J. Cosemans Dept. of Biochemistry Cardiovascular Research Institute Maastricht (CARIM) Maastricht University Medical Centre+, The Netherlands PDF: download this presentation (2.6 MB) "Confrontation cultures of embryonic stem cell-derived embryoid bodies and multicellular tumour spheroids: a novel in vitro model for the study of tumour- induced angiogenesis" N. Milosevic1, Finkensieper2, M. Hannig2, M. Wartenberg2, H. Sauer1 1 Department of Physiology, University of Giessen, Germany 2 Department of Internal Medicine I, University of Jena,Germany PDF: download this presentation (110 kb) "Organotypic in vitro skin cancer model" Suzan Commandeur, MSc Department of Dermatology, Leids Universitair Medisch Centrum PDF: download this presentation (4.4 MB) "Evaluation of toxicological effects of POPs using primary fish cell cultures" Liv Søfteland, Invar Eide and Pål A. Olsvik National Institute of Nutrition and Seafood Research PDF: download this presentation (2.3 MB) "Free Concentrations in In Vitro Cytotoxicity Assays" Nynke Kramer, Bas Blaauboer and Joop Hermens Institute for Risk Assessment Sciences, Division Toxicology, Universiteit Utrecht PDF: download this presentation (2.6 MB) "A Cell-Basec Assay For The Detection Of A Potent Algal Neurotoxin In Biological Matrices" Mirella Bellocci Università di Modena e Reggio Emilia, Modena, Italy PDF: download this presentation (1 MB) "Regulatory Acceptance and Use of in vitro Methods for Non-Clinical Testing of Human Medicinal Products" Dr. Sonja Beken Non-Clinical Assessor, Registration Department Federal Agency for Medicines and Health Products (FAMHP) PDF: download this presentation (940 kb) "Validation and Regulatory Acceptance" Susanne N. Boehn Laboratory for Alternative Methods Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany PDF: download this presentation (104 kb)		· eSi workshop 2008: photos
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